MDA-TOEPGA: A novel method to identify miRNA-disease association based on two-objective evolutionary programming genetic algorithm

The association between miRNA and disease has attracted more and more attention. Until now, existing methods for identifying miRNA related disease mainly rely on top-ranked association model, which may not provide a full landscape of association between miRNA and disease. Hence there is strong need of new computational method to identify the associations from miRNA group view. In this paper, we proposed a framework, MDA-TOEPGA, to identify miRNAdisease association based on two-objective evolutionary programming genetic algorithm, which identifies latent miRNAdisease associations from the view of functional module. To understand the miRNA functional module in diseases, the case study is presented. We have been compared MDA-TOEPGA with several state-of-the-art functional module algorithm. Experimental results showed that our method cannot only outperform classical algorithms, such as K-means, IK-means, MCODE, HC-PIN, and ClusterONE, but can also achieve an ideal overall performance in terms of a composite score consisting of f1, Sensitivity, and Accuracy. Altogether, our study showed that MDA-TOEPGA is a promising method to investigate miRNA-disease association from the landscapes of functional module.     

CDM-系列开窗导流式催化精馏模块在C4/C5醚化等反应中的工业应用

CDM-系列开窗导流式催化精馏模块具有优异的"催化反应"和"组分分离"双重功能,综合性能优于催化蒸馏组件CDP,是其升级换代产品。可应用于甲基叔丁基醚、轻汽油醚化、异丁烯叠合和叔丁醇脱水等工艺中,主要介绍CDM-系列开窗导流式催化精馏模块产品特点及在工业装置中的应用情况。     

基于VR技术的智能变电站运行仿真培训系统

为了更加真实、直观地呈现智能变电站的运行整体结构,构建基于VR技术的智能变电站运行仿真培训系统。该系统通过5个模块协同完成智能变电站运行仿真培训,结合实际变电站的设备情况,采用二维纹理映射方法完成变电站设备仿真建模;系统利用虚拟现实交互模块呈现培训场景,参与培训人员能够通过人机交互设备,实现场景漫游和相关培训内容操作。测试结果表明:该系统能够较好地模拟出智能变电站的实际运行情况,参与培训的人员可以身临其境地完成整个变电站的巡视,更真实、直观地呈现智能变电站的整体状态。     

Study on a new air-gap membrane distillation module for desalination

A new air-gap membrane distillation (AGMD) module for desalination with internal latent-heat-recovery which consisted of parallel hollow fiber membranes and heat exchange hollow fibers was successfully developed. The influences of feed flow rate, feed temperature and feed initial concentration on AGMD process were investigated. The vapor pressure polarization coefficient (η) was introduced to measure the reduction in the effective driving force for mass transfer with regard to the driving force imposed. Among all AGMD experiments, the maximum water vapor permeate flux (J_D) of 5.30 kg/m² h and the gained output ratio (GOR) of 5.70 were obtained. A theoretical model based on the mass and energy balances of the hot feed side was established to calculate the temperature and the local water vapor permeate flux distributions along the hollow fiber membrane, which showed that the temperature drop and local water vapor permeate flux drop were much larger at the upper part than those at the lower part of the membrane module in the hot feed side.     

基于可编程逻辑控制器的电镀工艺参数自动化监控

以可编程逻辑控制器(PLC)为控制核心,辅助相关执行元器件,对电镀过程中涉及的部分关键工艺参数实施自动化监控。分模块阐述了监控原理,并结合实验进行效果验证和评定。结果表明:应用PLC控制系统,可实现工艺参数自动化、实时、准确监控,并且可获得较理想的电镀质量。     

高反光率EVA胶膜的制备与性能研究

文章介绍了高反光率EVA胶膜的制备过程,并将其与常规EVA胶膜以及双玻组件用EVA胶膜进行封装组件功率及黄色指数变化效果对比分析。研究结果表明:采用高反射功能助剂改性方法制备的高反光率EVA胶膜,具有优异抗紫外辐射老化能力,同时能够提高组件的光电转换效率及功率。     

小型体化污水处理设备工艺研究

分析了我国农村和小城镇污水水质、水量的特点,以及目前一体化污水处理设备在农村和小城镇污水处理中应用时所存在的问题。提出了一种小型一体化污水处理设备（MST）,该设备在工艺上借鉴生物膜法中的生物接触氧化法和流动床工艺．采用模块化设计的理念,将气提反应模块代替传统二沉池。通过中试试验验证了该设备具有良好的去除有机物、氨氯和SS的效果,特别是出水SS的质量浓度能够稳定达到10mg／L以下。为我国农村和小城镇污水处理提供新的解决办法。     

改进型4Cr5Mo2MnV1Si压铸模块钢的球化处理

改进型4Cr5Mo2MnV1Si压铸模块钢采用传统“余热退火+正火+等温球化退火”工艺球化处理后,组织未达到技术要求,对其传统球化处理工艺做了改进,并对改进工艺处理试样的组织、硬度进行检测。结果表明,试验钢余热退火+正火+等温球化退火后,再经1010℃保温0.5 h炉冷至不同温度(820、790和760℃)保温1 h空冷处理后,显微组织均呈板条马氏体形态,基体上均匀弥散分布有碳化物颗粒,但硬度均高于400 HBW,未达到硬度小于240 HBW球化组织的要求。而经1010℃保温0.5 h空冷至室温,再820、790和760℃保温1 h回火空冷处理后,组织均为等轴铁素体上均匀分布着质点状碳化物,硬度分别为321、235和245 HBW,其中790℃回火效果最好,球化组织级别达到GB3,硬度小于240 HBW。因此,采用余热退火+正火+高温回火(790℃)代替余热退火+正火+等温球化退火可实现改进型4Cr5Mo2MnV1Si压铸模块钢的锻后球化处理。     

流体力学教学中的传统教学与网络多媒体教学

通过论述传统教学模式与多媒体网络教学模式的利弊 ,提出了在流体力学教学活动中既要弘扬传统教学的优点 ,又要融入现代多媒体网络教学 ,两者有机地结合起来 ,高效率、高质量地培养出优秀人才。     

ZXJ10(B)型交换机的日常维护

针对ZXJ10(B)型交换机进行日常维护的重要性,从交换理论知识、基本操作功能的掌握、频繁维护操作的运用、模块倒换问题的处理等方面介绍了对ZXJ10(B)型交换机日常维护的经验,以供参考。